Dr. Mohane Coumar

Assistant Professor

Centre for Bioinformatics

About
Research Area

Dr. S. Mohane Coumar, a native of Pondicherry, has received his Bachelor of Pharmacy from Kerala University, Masters in Pharmaceutical Chemistry and Ph.D. in Pharmaceutical Sciences from Punjab University, Chandigarh. He has over six years postdoctoral research training at National Health Research Institutes, Taiwan on anti-cancer drug design & development,. Two of his inventions are in Clinical development for the treatment of cancer in Taiwan. His current research includes, anti-cancer and anti-microbial drug discovery using various computational approaches such as computer-aided drug design, NGS data analysis and systems biology.

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Publications

Notable Publications

Hemant Arya, C. Suresh Yadav, Shu-Yu Lin, Safiulla Basha Syed, Sathananthan Kannadasan, Hsing-Pang Hsieh, Sorokhaibam Sureshkumar Singh, Padma Raj Gajurel, and Mohane Selvaraj Coumar* Design of a potent anticancer lead inspired by natural products from traditional Indian medicine. J. Biomol. Struct. Dyn, 2020,. 38, 3563-3577 [JCR 2017 IF: 3.1]

M Ramya Chandar Charles, Arun Mahesh, Shu-YuLin, Hsing-Pang Hsieh, Arunkumar Dhayalan*, Mohane Selvaraj Coumar* Identification of novel quinoline inhibitors for EHMT2/G9a through virtual screening Biochimie, 2020, 168, 220-230. [JCR 2018 IF: 3.2]

Safiulla Basha Syed, Hemant Arya, I-Hsuan Fu, Teng-Kuang Yeh, Latha Periyasamy, Hsing-Pang Hsieh, and Mohane Selvaraj Coumar* Targeting P-glycoprotein: Investigation of piperine analogs for overcoming drug resistance in cancer. Scientific Reports 2017, 7, 7972 [JCR 2017 IF: 4.3]

Sailu Sarvagalla, Vivek Kumar Singh, Yi-Yu Ke, Hui-Yi Shiao, Wen-Hsing Lin, Hsing-Pang Hsieh, John T. A. Hsu, and Mohane Selvaraj Coumar*. Identification of ligand efficient, fragment-like hits from an hts library: structure-based virtual screening and docking investigations of 2H- and 3H-pyrazolo tautomers for aurora kinase a selectivity. J. Comput. Aided Mol. Des. 2015, 29, 89-100 [JCR 2017 IF: 3.0]

Mohane Selvaraj Coumar, Chang-Ying Chu, Cheng-Wei Lin, Hui-Yi Shiao, Yun-Lung Ho, Randheer Reddy, Santhosh Kumar Chittimalla, Chun-Hwa Chen, Tzu-Wen Lien, Chin-Ting Huang, Wen-Hsing Lin, John T.-A. Hsu, Jiun-Shyang Leou, Yi-Hui Peng, Jian-Sung Wu, Su-Ying Wu, Chun-Chen Liao, Yu-Sheng Chao, and Hsing-Pang Hsieh. “Fast-forwarding kinase drug discovery: aurora and EGFR kinase inhibitor lead identification” J Med Chem 2010, 53, 4980-4988. [JCR 2017 IF: 6.3]

Awards & Achievements​

Nominated by Pondicherry University for fourth Visitors award for research (Basic and Applied sciences) 2018
NHRI (Taiwan) International travel grant awards to attend scientific conference in US (2005 & 2006), China (2008) and Singapore (2009)
NHRI Research day presentation award 2010

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