Dr. Mohane Coumar
About
Research Area
Dr. S. Mohane Coumar, a native of Pondicherry, has received his Bachelor of Pharmacy from Kerala University, Masters in Pharmaceutical Chemistry and Ph.D. in Pharmaceutical Sciences from Punjab University, Chandigarh. He has over six years postdoctoral research training at National Health Research Institutes, Taiwan on anti-cancer drug design & development,. Two of his inventions are in Clinical development for the treatment of cancer in Taiwan. His current research includes, anti-cancer and anti-microbial drug discovery using various computational approaches such as computer-aided drug design, NGS data analysis and systems biology.
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Publications
Notable Publications
Sree Karani Kondapuram and Mohane Selvaraj Coumar*. Pan-cancer gene expression analysis: Identification of deregulated autophagy genes and drugs to target them. Gene 2022, 844, 146821. [JCR 2020 IF: 3.9; Citations:].
Chandar Charles, M. Ramya; Li, Mu-Chun; Hsieh, Hsing-Pang*; Coumar, Mohane*. Mimicking H3 substrate arginine in the design of G9a lysine methyltransferase inhibitors for cancer therapy: a computational study for structure-based drug design. ACS Omega, 2021, 6(9), 6100-6111. [JCR 2020 IF: 4.1; Citations: 1].
Sailu Sarvagalla, Tzu-Yu Lin, Sree Karani Kondapuram, Chun Hei Antonio Cheung, and Mohane Selvaraj Coumar*. Survivin - Caspase protein-protein interaction: experimental evidence and computational investigations to decipher the hot spot residues for drug targeting. Journal of Molecular Structure. 2021, 1229, 129619. [JCR 2020 IF: 3.8; Citations: 5].
M Ramya Chandar Charles, Arun Mahesh, Shu-YuLin, Hsing-Pang Hsieh, Arunkumar Dhayalan, Mohane Selvaraj Coumar* Identification of novel quinoline inhibitors for EHMT2/G9a through virtual screening Biochimie, 2020, 168, 220-230. [JCR 2020 IF: 4.4; Citations: 9].
Safiulla Basha Syed, Hemant Arya, I-Hsuan Fu, Teng-Kuang Yeh, Latha Periyasamy, Hsing-Pang Hsieh, and Mohane Selvaraj Coumar* Targeting P-glycoprotein: Investigation of piperine analogs for overcoming drug resistance in cancer. Scientific Reports 2017, 7, 7972 [JCR 2017 IF: 5.0; Citations: 67].
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