Dr. C. Thirunavukkarasu

Associate Professor

Department of Biochemistry and Molecular Biology

About
Research Area

I have been trained in the leading Thomas E Starzl, Transplantation Institute, University of Pittsburgh, PA, USA under renowned hepatologist Prof. CR. Gandhi. The institute is named based on the scientist Prof. Starzl who successfully carried out the first human liver transplantation. My thirst in higher learning and eagerness to get trained under Prof. S. Gupta made me to land in Albert Einstein College of Medicine of Yeshiva University, Newyork, USA. After gaining rich experiences from the renowned institute and the eminent scientists  my research area fixates on combating liver diseases, such as hepatocarcinogenesis, liver tumor niche, fatty liver disorders, and hepatotoxicity, employing nanotechnology and biotechnological approach. My contributions have rewarded me the awards from recognized, reputed and prestigious academic bodies/societies. My passion towards teaching starts from foundation course such as “Cell Biology” to advanced level emphasizing the needs of the diseases free society such as “Cancer Biology”. With ample experience, I am a sedulous fervent researcher and believes in strenuous exertion rather than fortuity.

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Publications

Notable Publications

Nithyananthan S and Thirunavukkarasu C. Arsenic trioxide, a cancer chemo drug hamper fibrotic liver regeneration by interrupting oxidative stress rekindling and stellate cell rejuvenation. Journal of Cellular Physiology. 2020: 235; 1222-1234. (IF 4.52)

Preedia Babu E, Subastri A , Suyavaran A, Nithyananthan S, Suresh Kumar M, Premkumar K, Bharathidasan R, and Thirunavukkarasu C. Anticancer potential of ZnO nanoparticle-ferulic acid conjugate on Huh-7 and HepG2 cells and diethyl nitrosamine induced hepatocellular cancer on Wistar albino rat. Nanomedicine-Nanotechnology Biology and Medicine 2018: 14 (2); 415-428. (IF 6.500)

Suyawaran A and Thirunavukkarasu C. Preconditioning methods in the management of hepatic ischemia reperfusion- induced injury: update on molecular and future perspectives. Hepatology Research. 2017: 47(1); 31-48. (IF 3.415)

Thirunavukkarasu C, Watkins SC and Gandhi CR. Endotoxin stimulate cytokine and nitric oxide production in rat hepatic stellate cells via p38 MAPK and reactive oxygen species. Hepatology. 2006: 44 (2); 389-398. (IF – 11.335)

Thirunavukkarasu C, Yang Y, Subbotin VM, Harvey SAK, Fung J and Gandhi CR. Endothelin receptor antagonist TAK-044 arrests and reverses the development of carbon tetrachloride-induced cirrhosis in rat. GUT. 2004: 53 (7); 1010-1019. (IF –14.614)

Awards & Achievements​

“Fellow” (FABMS) from Indian Association of Biomedical Scientists.
Young scientist travel award by American Society of Pharmacology and Experimental Therapeutics, in Experimental Biology 2005, San Diego, April 2-6, USA.
Postdoctoral travel award by American Society of Biochemistry and Molecular Biology, in Experimental Biology 2003, San Diego, April 11-15, USA.

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