Dr. V. Thillai Sekar
About
Research Area
Dr. V. Thillai Sekar, Associate Professor in the Department of Microbiology, Pondicherry University, and awarded Ph.D. in Microbiology, University of Madras, Chennai, India in 2007. He was awarded with visiting scientist fellowship from National Science Council, Taiwan and served as Postdoctoral fellow in the University of California, Irvine and Stanford University, USA for 6 years. He also served as Research Scientist in Stanford University and as Senior Research Scientist in the University of Texas Southwestern Medical Center, Dallas, USA for over 8 years. He was member of various scientific societies including World Molecular Imaging Society (WMIS), American Society of Gene and Cell Therapy (ASGCT), and Society for Immunotherapy of Cancer (SITC). He was awarded with Visiting Scientist fellowship award, ICMIC award and various travel grant awards. His current research focus on developing antibody mimetics such as nanobody and affibody, and designing genetically encoded optical imaging sensors to screen bio-drugs from microbes, and other natural sources.
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Publications
Notable Publications
Sekar TV, Elghonaimy E, Swancutt KL, Whitney M, Aguilera TA (2021). In Vivo selection of nanobodies to target the tumor immune microenvironment for immunotherapy development. BioRxiv. https://doi.org/10.1101/2021.05.26.445719
Sekar TV, Foygel K, Devulapally R, Kumar V, Malhotra S, Massoud TF, Paulmurugan R (2016). Molecular Imaging Biosensor Monitors p53 Sumoylation in Cells and Living Mice. Analytical Chemistry. 88(23). 11420-11428
Sekar TV, Foygel K, Massoud TF, Gambhir, SS, Paulmurugan R (2016). A transgenic mouse model expressing an ERα folding biosensor reveals the effects of Bisphenol A on estrogen receptor signaling. Scientific Reports. 6, 34788
Sekar TV, Foygel K, Gelovani JG, Paulmurugan R (2015). Genetically Encoded Molecular Biosensors to Image Histone Methylation in Living Animals. Analytical Chemistry. 2015 Jan 20;87(2):892-9.
Sekar TV, Foygel K, Devulapally R, Paulmurugan R (2015). Degron Protease Blockade Sensor to Image Epigenetic Histone Protein Methylation in Cells and Living Animals. ACS Chemical Biology. 2015 Jan 16;10(1):165-74.
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