Dr. Rajaneesh Anupam

Associate Professor

Department of Biochemistry and Molecular Biology

About
Research Area

Rajaneesh Anupam obtained his integrated MS+PhD degree in Biochemistry, Molecular and Cellular Biology from the Department of Chemistry and Biochemistry at Ohio University in 2007. His doctoral research was focused on understanding a bacterial riboswitch and targeting it with small molecules to develop novel antibacterials agents. He worked as a Postodoctoral Research Fellow and Research Scientist at The Ohio State University for more than 5 years. During which He studied the pathiobology of a Human T lymphotropic virus type 1 (HTLV-1), an oncogenic retrovirus, using various molecular biology techniques. In 2013 he joined as an Assistant Professor in Department of Biotechnology at Dr. Harisingh Gour Vishwavidyalaya (A Central University), Sagar, Madhya Pradesh. He joined the Department of Biochemistry and Molecular Biology at Pondicherry University as an Associate Professor in 2022. Rajaneesh is a Molecular Virologist and his research interest is to understand the contribution of viral genes in the viral pathogenesis. Specifically understanding and targeting essential viral-host interactions to develop antiviral drugs. His lab is also interested in invesitgating the potential of garlic organosulphur compounds as novel antibacterial agents.

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Publications

Notable Publications

Bhatwalkar SB, Mondal R, Krishna SBN, Adam JK, Govender P, Anupam R. Antibacterial Properties of Organosulfur Compounds of Garlic (Allium sativum). Front Microbiol. 2021 Jul 27;12:613077. doi: 10.3389/fmicb.2021.613077.

Lyngdoh DL, Shukla H, Sonkar A, Anupam R, Tripathi T.Portrait of the Intrinsically Disordered Side of the HTLV-1 Proteome.ACS Omega. 2019 Jun 7;4(6):10003-10018. doi: 10.1021/acsomega.9b01017.

Bhatwalkar SB, Gound SS, Mondal R, Srivastava RK, Anupam R.Anti-biofilm and Antibacterial Activity of Allium sativum Against Drug Resistant Shiga-Toxin Producing Escherichia coli (STEC) Isolates from Patient Samples and Food Sources. Indian J Microbiol. 2019 Jun;59(2):171-179. doi: 10.1007/s12088-019-00784-3.

Namdev P, Lyngdoh DL, Dar HY, Chaurasiya SK, Srivastava R, Tripathi T, Anupam R.Intrinsically Disordered Human T Lymphotropic Virus Type 1 p30 Protein: Experimental and Computational Evidence. AIDS Res Hum Retroviruses. 2019 May;35(5):477-487. doi: 10.1089/AID.2018.0196.

Anupam R, Datta A, Kesic M, Green-Church K, Shkriabai N, Kvaratskhelia M, Lairmore MD. Human T-lymphotropic virus type 1 p30 interacts with REGgamma and modulates ATM (ataxia telangiectasia mutated) to promote cell survival. J Biol Chem. 2011 Mar 4;286(9):7661-8. doi: 10.1074/jbc.M110.176354.

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