Dr. Agilan Balupillai

Assistant Professor

Department of Biotechnology

About
Research Area

I received Ph.D. from the Department of Biochemistry and Biotechnology, Annamalai University, India, and pursued postdoctoral fellowships at Thiruvalluvar University, Vellore, India, offered by DSK-UGC Scheme. Also, I visited at Hospital of Maisonneuve Rosemont, affiliated with the University of Montreal, Montreal, Canada, for a postdoctoral fellowship. My doctoral study investigates molecular mechanisms of UV radiation-mediated skin inflammation, photoaging, and skin cancer and its countermeasures. Also, I significantly contributed to cancer multidrug resistance in cancer cells. My postdoctoral work investigated the codelivery of small molecules with chemotherapeutical drug-loaded liposomes to improve the chemotherapy in triple-negative breast cancer cells and tumor xenograft models. My long-term goal is to identify the binding partner that regulates base excision and nucleotide excision repair during the chemotherapeutics-mediated DNA damage in cancer cells.

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Notable Publications

Opuntiol Prevents Photoaging of Mouse Skin via Blocking Inflammatory Responses and Collagen Degradation

Polydatin Encapsulated Poly [Lactic-co-glycolic acid] Nanoformulation Counteract the 7, 12-Dimethylbenz [a] Anthracene Mediated Experimental Carcinogenesis through the Inhibition of Cell Proliferation

Caffeic acid prevents UVB radiation induced photocarcinogenesis through regulation of PTEN signaling in human dermal fibroblasts and mouse skin

Linalool prevents oxidative stress activated protein kinases in single UVB exposed human skin cells

Caffeic acid inhibits chronic UVB induced cellular proliferation through JAK-STAT3 signaling in mouse skin

Awards & Achievements​

Awarded in UGC-DSK postdoctoral fellowship for the year April 2019-March 2022 (File No: F.4-­2/2006(BSR)/BL/18-19/0113Dt.06.02.2019 (79th list)
Awarded in postdoctoral fellowship in Department of Medicine, Masionneuve Rosemont Hopital, Montreal, Canada on 2018
Awarded in National Postdoctoral fellowship (nPDF) in Scientific and Engineering Research Board (SERB) fellowship for the year April 2017 (File No: PDF/2017/000118/LS.

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