Dr. Arunkumar Dhayalan

Assistant Professor

Department of Biotechnology

About
Research Area

Dr. Dhayalan completed his PhD in 2009 with special distinction from the Jacobs University, Germany under the guidance of Prof. Dr. Albert Jeltsch. He joined Pondicherry University as Assistant Professor in the year 2010. In Pondicherry University, Dr. Dhayalan is working in two major areas viz. (i) Histone arginine methylation mediated epigenetic signalling and (ii) Functional characterization of DEAD box family of RNA helicases. His lab has been funded by DBT, UGC, CSIR, SERB-DST and BRNS. He has published more than 30 research articles in well-reputed journals. Dr. Dhayalan holds Associate Editorship in the research journal “BMC Biochemistry”.

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Publications

Notable Publications

Mahesh A, Khan MIK, Govindaraju G, Verma M, Awasthi S, Chavali PL, Chavali S, Rajavelu A & Dhayalan A (2020) SET7/9 interacts and methylates the ribosomal protein, eL42 and regulates protein synthesis. BBA-Molecular Cell Research, 1867, 118611-118623.

Awasthi S, Chakrapani B, Mahesh A, Chavali PL, Chavali S & Dhayalan A (2018) DDX39B promotes translation through regulation of pre-ribosomal RNA levels. RNA Biology, 15, 1157-1166.

Awasthi S, Verma M, Mahesh A, Khan MK, Govindaraju G, Rajavelu A, Pavithra L. Chavali PL, Chavali S & Dhayalan A (2018) DDX49 is an RNA helicase that affects translation by regulating mRNA export and the levels of pre-ribosomal RNA. Nucleic Acids Research, 46, 6304-6317.

Verma M, Charles RCM, Chakrapani B, Coumar MS, Govindaraju G, Rajavelu A, Chavali S, Dhayalan A. (2017) PRMT7 Interacts with ASS1 and Citrullinemia Mutations Disrupt the Interaction. J Mol Biol. 429, 2278-2289.

Dhayalan, A., Rajavelu, A., Rathert, P., Tamas, R., Jurkowska, RZ., Ragozin, S., Jeltsch, A. (2010) The Dnmt3A PWWP domain reads histone 3 lysine 36 trimethylation and guides DNA methylation. J. Biol. Chem 285, 26114-26120.

Awards & Achievements​

Early Career Research Award for the year of 2017 from Science and Engineering Research Board (SERB), DST, Government of India.
UGC Research Award for the year of 2015 from University Grants Commission (UGC), Government of India.
Innovative Young Biotechnologist Award, 2010 from Department of Biotechnology (DBT), Government of India.

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