Dr. Madhu Dyavaiah
About
Research Area
I am teaching Proteomics, Genomics, and Clinical Biochemistry subjects for PG students. We have published 41 international research papers and edited three books with an H index of 23. My research area is focused on DNA damage response, Translation regulation and anti-aging. We are studying the therapeutic potentials of natural compounds to target gene-deficient cells using the Saccharomyces Cerevisiae gene deletion library and mammalian cell culture model. In addition, the anti-aging properties of natural compounds and their mechanisms of action are also being studied.
We have published our research work in reputed journals such as Biogerontology, FEMS yeast research and FEBS Letters. I have completed 3-projects and 1 is ongoing, guided 3-Ph.D students, and received many awards, including the TECT best-published paper award (2025). My previous experience at IISc, Bangalore, New York State Dept. of Health, and State University of New York, USA helped me enhance my teaching and research.
Notable & Recent Publications
"Bhavana Veerabhadrappa, Sudharshan SJ, Nagashree N. Rao and Madhu Dyavaiah, “Loss of tRNA methyltransferase 9 and DNA damage response genes in yeast confers sensitivity to aminoglycosides”, FEBS Letters, 597(8):1149-1163, 2023. Impact factor - 4.124 "
Bhavana Veerabhadrappa, Subasri Subramaniyan, Sudharshan SJ and Madhu Dyavaiah, Evaluating the genetic basis of anti-cancer property of Taxol in Saccharomyces cerevisiae model, FEMS Microbiology Letters. 6;368(13), 2021, Impact factor - 2.2
Sudharshan SJ, and Madhu Dyavaiah, Astaxanthin protects oxidative stress mediated DNA damage and enhances longevity in Saccharomyces cerevisiae, Biogerontology, 22(1):81-100, 2020. Impact factor – 4.4
Sudharshan SJ, Bhavana Veerabhadrappa, Subasri Subramaniyan, Madhu Dyavaiah, Astaxanthin enhances the longevity of Saccharomyces cerevisiae by decreasing oxidative stress and apoptosis, FEMS Yeast Research, 9 (1), 113, 2019. Impact factor – 2.4
Subasri Subramaniyan, Phaniendra Alugoju, Sudharshan Sj, Bhavana Veerabhadrappa, Madhu Dyavaiah, Magnolol protects Saccharomyces cerevisiae antioxidant-deficient mutants from oxidative stress and extends yeast chronological life span, FEMS Microbiology Letters, 1;366(8):65, 2019 Impact factor – 2.2
