Dr. C. R. Ramanathan
About
Research Area
Group actively involving in creating new chiral molecules for both asymmetric organ catalysis and transition metal catalyzed reactions to generate a library of chiral molecules. Simple and convenient methods have been developed through C-C bond forming reactions promoted by Lewis / Bronsted acid to construct
nitrogen heterocycles, natural products, and natural product-like molecules. Synthesized natural products, natural product-like molecules, and small molecules have been evaluated for their anti-cancer activity. Our research group will continue to explore the development of new chiral catalysts, new synthetic
methodologies, and drug discovery.
Asymmetric Synthesis and drug discovery
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years
Teaching Experience
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Research (Guided & On-roll)
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Projects (Completed & On-going)
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Publications
Notable & Recent Publications
Karthick, M.; Someshwar, N.; Mariappan, C. R.; Ramasubbu, A.; Ramanathan, C. R., Chiral 3,3’-diaroyl BINOL phosphoric acids: syntheses and evaluation in asymmetric transfer hydrogenation, photophysical, and electrochemical studies, Org. Biomol. Chem., 23, 3112-3125, 2025.– Impact Factor (2022): 3.2.
Karthick, M.; Sushmita, G.; Ramanathan, C. R., Decarboxylative iodination and Suzuki-Miyaura coupling reactions to access chiral 3,3ʹ-diaryl-1,1ʹ-bi-2-naphthols, J. Org. Chem., 89, 291-303, 2024.– Impact Factor (2023): 3.4.
Rao, R. S.; Sahani, A.; Ali, S. H.; Pradhan, S.; Ramanathan, C. R., γ‐Al2O3/triflic acid as cooperative catalysts for the tandem Michael addition/carbocyclization: An easy access to 2‐substituted pyrrolo [2, 1‐a] isoquinolines and 3‐substituted pyrrolidine‐2, 5‐diones, J. Heterocycl. Chem., 58, 1415-1428, 2021. - Impact Factor (2022) - 2.4
Karthick, M.; Abi, E. K.; Someshwar, N.; Anthony, S. P.; Ramanathan, C. R., NaHSO4/SiO2 catalyzed generation of o-quinone/o-thioquinone methides: synthesis of arylxanthenes/ arylthioxanthenes via oxa-6π–electrocyclization, Org. Biomol. Chem., 18, 8653, 2020. – Impact Factor (2022): 3.2.
Venkatanna, K.; Yeswanth Kumar, S.; Karthick, M.; Padmanaban, R.; Ramanathan, C. R., A chiral bicyclic skeleton-tethered bipyridine–Zn(OTf)2 complex as a Lewis acid: enantioselective Friedel–Crafts alkylation of indoles with nitroalkenes, Org. Biomol. Chem., 17, 4077, 2019. Impact Factor (2022): 3.2.
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