Dr. Agilan Balupillai
About
Research Area
I received Ph.D. from the Department of Biochemistry and Biotechnology, Annamalai University, India, and pursued postdoctoral fellowships at Thiruvalluvar University, Vellore, India, offered by DSK-UGC Scheme. Also, I visited at Hospital of Maisonneuve Rosemont, affiliated with the University of Montreal, Montreal, Canada, for a postdoctoral fellowship. I have published over 37 research articles in highly regarded peer-reviewed journals. My research expertise lies in UV radiation-induced skin inflammation, photoaging, and skin cancer, along with their therapeutic interventions. Currently, my work focuses on identifying novel genes involved in regulating multidrug resistance pathways in cancer cells.
Cancer Multidrug resistance and Radiation Biology
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years
Teaching Experience
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Research (Guided & On-roll)
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Publications
Notable & Recent Publications
Velaiyan M, Muthusamy R, Kativa M, Annamalai A, Govindhan A, Punniyakotti P, Balupillai A. Gallic acid-loaded chitosan nanoparticles enhance the DNA damage and apoptotic features through inhibiting flap endonuclease-1 in triple-negative breast cancer cells. Environ Toxicol. 2024;39(8):4171-4183.
Wei J, Balupillai A, Annamalai A, Selvababu AP, David E. Nobiletin enhances peroxiredoxin- 1, preventing UVA radiation-induced oxidative stress and photoaging in human skin epidermal keratinocytes. Journal of Functional Foods. 2024;114:106066
Vijayalakshmi S, Mariadoss AV, Ramachandran V, Shalini V, Agilan B, Sangeetha CC, Balu P, Kotakadi VS, Karthikkumar V, Ernest D. Polydatin encapsulated poly [lactic-co-glycolic acid] nanoformulation counteract the 7, 12-dimethylbenz [a] anthracene mediated experimental carcinogenesis through the inhibition of cell proliferation. Antioxidants. 2019;8(9):375.
Wang S, Jiang K, Muthusamy R, Kalaimani S, Selvababu AP, Balupillai A, Narenkumar J, jeeva Jeevakaruniyam S. Protosappanin-B suppresses human melanoma cancer cell growth through impeding cell survival, inflammation and proliferative signaling pathways. Process Biochemistry. 2022; 122:78-85.
Begum N, Rajendra Prasad N, Kanimozhi G, Agilan B. Apigenin prevents gamma radiation-induced gastrointestinal damages by modulating inflammatory and apoptotic signalling mediators. Natural Product Research. 2022;36(6):1631-5.
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