Dr. Anitha. T.S.
About
Research Area
Dr. Anitha T.Sโs research is centered on cancer biology and therapeutics, with a primary focus on glioblastoma and hepatocellular carcinoma. She also explores the emerging impact of microplastics on cancer progression. Her work aims to develop translational cancer therapies by investigating novel drug-targetable signaling pathways and the role of oxidative stress in tumor development.
She completed her Ph.D. at the Department of Animal Sciences, School of Life Sciences, Bharathidasan University, where she studied the molecular basis of oxidative stress-induced cataractogenesis and the impact of traditional therapeutic interventions. She began her scientific research career in 2015 as a Scientist at the Central Inter-Disciplinary Research Facility (CIDRF), Sri Balaji Vidyapeeth (Deemed to-be University), Puducherry, where she spent seven years investigating drug repurposing strategies for glioma, focusing on therapeutic efficacy and synergy with standard treatments.
In 2022, she joined Pondicherry University as an Assistant Professor, where she is actively engaged in both teaching and research. Her current research aims to translate foundational scientific discoveries into molecular medicine for cancer treatment, with the broader goal of improving patient outcomes and survival rates. Her expertise includes both in vitro and in vivo preclinical cancer models, particularly xenograft-induced cancer models, and she has published her findings in reputed peer-reviewed journals such as Scientific Reports, Frontiers in Pharmacology, Life Sciences etc. She has received research funding from both institutional and national bodies, including the Indian Council of Medical Research (ICMR) and the Department of Science, Technology, and Environment (DSTE), Government of Puducherry and maintains collaborations with national and international research groups and R&D labs.
In 2024, she was awarded the ICMR-DHR Long-term International Fellowship for Young Biomedical Scientists and received advanced research training at the University of Paris-Est Crรฉteil, France, where she gained hands-on experience in using the chick embryo model for drug toxicity studies and as a cancer research model. She is also actively involved in academiaโindustry collaborative projects in cancer research.
Notable & Recent Publications
Biswas I, Precilla SD, Kumar A, Sekhar MM, Renu M, Anitha TS*. Anti-tumor efficacy and safety of AEV01 in preclinical glioblastoma and hepatocellular carcinoma models. Sci Rep 2025; 15: 6980.
Nivedita Jha, Megha Prasanth, Daisy Precilla S, Sivachandran R, Ramprasath A, Rajkumar M, Anitha TS*. Microplastics and Cancer: A Comprehensive Review of Their Impact on Tumor Progression and Mechanisms of Carcinogenesis. Journal of Environmental Pathology, Toxicology and Oncology. 2024 10.1615/JEnvironPatholToxicolOncol.2025054888 (Published online)
Kuduvalli SS, Daisy PS, Vaithy A, Purushothaman M, Ramachandran Muralidharan A, Agiesh KB, Mezger M, Antony JS, Subramani M, Dubashi B, Biswas I, Guruprasad KP, Anitha TS*. A combination of metformin and epigallocatechin gallate potentiates glioma chemotherapy in vivo. Front Pharmacol. 2023 Mar 21;14:1096614.
Kuduvalli SS, Senthilathiban DP, Biswas I, Antony JS, Subramani M, Anitha TS*. The synergistic anti-Warburg efficacy of temozolomide, metformin, and epigallocatechin gallate in glioblastoma. J Toxicol Appl Pharmacol. 2024; 493:117146.
Biswas I, Precilla S D, Kuduvalli SS, K B, R S, Anitha TS*. Ultrastructural and immunohistochemical insights on the anti-glioma effects of a dual-drug cocktail in an in vivo experimental model. J Chemother. 2024 Jan 19:1-14.