ARUNKUMAR DHAYALAN Assistant Professor

Profile Picture

  • Department of Biotechnology
  • School of Life Sciences
  • arun.dbt@gmail.com,arun.dbt@pondiuni.edu.in

Academic Activity

Academic Activity Picture1

Academic Activity Picture2

Educational Qualification (UG,PG & Higher Order)

S.No Degree Subject/Title of thesis University/Board Year of Passing
1 Ph.D Molecular Epigenetics Jacobs University, Bremen, Germany 2009
2 M.Sc Biotechnology Pondicherry University 2002
3 B.Sc Biochemistry University of Madras 2000

Area of Specializaion

Molecular Epigenetics

Awards / Prizes Conferred

S.No Name / Title of the Award Type Name of the Agency conferred the Award Year of the Award Amount for Cash Award
1 Best Teacher Award REGIONAL Pondicherry University 2019 Nil
2 Best Teacher Award REGIONAL Pondicherry University 2018 Nil
3 Early Career Research Award NATIONAL SERB-DST, Government of India 2017 Nil
4 Best Teacher Award REGIONAL Pondicherry University 2016 Nil
5 Best Teacher Award REGIONAL Pondicherry University 2015 Nil
6 UGC Research Award NATIONAL University Grants Commission, Government of India 2015 Nil
7 Best Teacher Award REGIONAL Pondicherry University 2014 Nil
8 Best Teacher Award REGIONAL Pondicherry University 2013 Nil
9 Young Scientist Award NATIONAL SERB-DST, Government of India 2012 Nil
10 Best Teacher Award REGIONAL Pondicherry University 2012 Nil
11 Best Teacher Award REGIONAL Pondicherry University 2011 Nil
12 Innovative Young Biotechnologist Award NATIONAL Department of Biotechnology, Government of India 2010 3 Lakhs
13 Ph.D fellowship INTERNATIONAL DFG (German Research Foundation) 2005 NA

Teaching Experience

S.No Designation Department/Centre Institution
1 Assistant Professor Biotechnology Pondicherry University

Research Experience

S.No Designation Department/Centre Institution Area of Research
1 Postdoctoral Fellow Biochemistry Jacobs University, Bremen, Germany. Epigenetics
2 Assistant Professor Biotechnology Pondicherry University Epigenetics

Industry Experience

S.No Designation Company/Corporate Nature of Work

Contribution towards Innovation

S.No Name of the Work/Contribution Specialization Remarks

Patent Details

S.No Title Status Patent Number Year of Award Type Commercialized Status

Papers Published in UGC Approved Journals

S.No Title Name of the Authors as per the order in Paper Journal Name Volume, Issue & Page Nos. Year Impact Factor

Papers Published in Peer Reviewed Journals

S.No Title Name of the Authors as per the order in Paper Journal Name Volume, Issue & Page Nos. Year Impact Factor
1 SET7/9 interacts and methylates the ribosomal protein, eL42 and regulates protein synthesis. Mahesh A, Khan MIK, Govindaraju G, Verma M, Awasthi S, Chavali PL, Chavali S, Rajavelu A & Dhayalan A Biochim Biophys Acta Mol Cell Res 1867, 118611-118623 2020 4.7
2 Identification of novel quinoline inhibitor for EHMT2/G9a through virtual screening Chandar Charles MR, Mahesh A, Lin SY, Hsieh HP, Dhayalan A* & Coumar MS Biochimie 168, 220-230 2020 3.4
3 Insights for the design of protein lysine methyltransferase G9a inhibitors. Charles RCM, Dhayalan A, Hsieh HP & Coumar MS Future Medicinal Chemistry 11, 993-104 2019 3.6
4 Structure, luminescence, mechanical and in vitro behavior of zirconia toughened alumina due to terbium substitutions. Ponnilavan V, Khan MIK, Dhayalan A & Kannan S Materials Science & Engineering C 102, 810-819 2019 5.0
5 Structural and bio-mineralization features of alumina zirconia composite influenced by the combined Ca2+ and PO43- additions. Ponnilavan V, Vasanthavel S, Khan MIK, Dhayalan A & Kannan S Materials Science & Engineering C 98, 381-391 2019 5.0
6 Bactericidal and fungistatic activity of peptide derived from GH18 domain of prawn chitinase 3 and its immunological functions during biological stres Ravichandran G, Kumaresan V, Mahesh A, Dhayalan A, Arshad A, Arasu MV, Al-Dhabi NA, Pasupuleti M, Arockiaraj J. International Journal of Biological Macromolecules 106, 1014-1022 2018 4.8
7 Identification of protein lysine methylation readers with a yeast three-hybrid approach Rawłuszko-Wieczorek AA, Knodel F, Tamas R, Dhayalan A & Jeltsch A Epigenetics & Chromatin doi: 10.1186/s13072-018-0175-3 2018 4.2
8 DDX49 is an RNA helicase that affects translation by regulating mRNA export and the levels of pre-ribosomal RNA Awasthi S, Verma M, Mahesh A, Khan MK, Govindaraju G, Rajavelu A, Pavithra L. Chavali PL, Chavali S & Dhayalan A Nucleic Acids Research 46, 12 & 6304-6317 2018 11.1
9 DDX39B promotes translation through regulation of pre-ribosomal RNA levels Awasthi S, Chakrapani B, Mahesh A, Chavali PL, Chavali S & Dhayalan A RNA Biology 15, 9 & 1157-1166 2018 5.5
10 PRMT7 Interacts with ASS1 and Citrullinemia Mutations Disrupt the Interaction Verma M, Charles RCM, Chakrapani B, Coumar MS, Govindaraju G, Rajavelu A, Chavali S & Dhayalan A. Journal of Molecular Biology 429, 15 & 2278-2289 2017 5.1
11 Iron doped β-Tricalcium phosphate: Synthesis, characterization, hyperthermia effect, biocompatibility and mechanical evaluation Singh RK, Srivastava M, Prasad NK, Awasthi S, Dhayalan A & Kannan S. Mater Sci Eng C Mater Biol Appl. 78, 715-726 2017 5.0
12 Pellino-1 derived cationic antimicrobial prawn peptide: Bactericidal activity, toxicity and mode of action Ravichandran G, Kumaresan V, Arasu MV, Al-Dhabi NA, Ganesh MR, Mahesh A, Dhayalan A, Pasupuleti M & Arockiaraj J. Molecular Immunology 78, 171-182 2016 3.1
13 Deposition, structure, physical and invitro characteristics of Ag-doped β-Ca3(PO4)2/chitosan hybrid composite coatings on Titanium metal. Singh RK, Awasthi S, Dhayalan A, Ferreira JM, Kannan S. Mater Sci Eng C Mater Biol Appl. 62, 692-701 2016 5.0
14 The Tudor domain of the PHD finger protein 1 is a dual reader of lysine trimethylation at lysine 36 of histone H3 and lysine 27 of histone variant H3t Kycia I, Kudithipudi S, Tamas R, Kungulovski G, Dhayalan A & Jeltsch A. Journal of Molecular Biology 426, 8 & 1651-1660 2014 5.1
15 The SET8 H4K20 protein lysine methyltransferase has a long recognition sequence covering seven amino acid residues Kudithipudi, S., Dhayalan, A., Kebede, AF. & Jeltsch, A. Biochimie 94, 11 & 2212-2218 2012 3.4
16 Application of Celluspots peptide arrays for the analysis of the binding specificity of epigenetic reading domains to modified histone tails Bock, I., Kudithipudi, S., Tamas, R., Kungulovski, G., Dhayalan, A. & Jeltsch, A. BMC Biochemistry 12, 48 & 1-12 2011 1.3
17 The ATRX-ADD domain binds to H3 tail peptides and reads the combined methylation state of K4 and K9 Dhayalan, A., Tamas, R., Bock, I., Tattermusch, A., Dimitrova, E., Kudithipudi, S., Ragozin, S. & Jeltsch, A Human Molecular Genetics 20, 11 & 2195-2203 2011 4.5
18 Specificity analysis based identification of new methylation targets of the SET7/9 protein lysine methyltransferase Dhayalan, A., Kudithipudi, S., Rathert, P. & Jeltsch, A. Chemistry & Biology 18, 1 & 111-120 2011 6.8
19 Detailed specificity analysis of antibodies binding to modified histone tails with peptide arrays Bock, I., Dhayalan, A., Kudithipudi, S., Brandt, O., Rathert, P. & Jeltsch, A. Epigenetics 6, 2 & 256-263 2011 4.2
20 Chromatin methylation activity of Dnmt3a and Dnmt3a/3L is guided by interaction of the ADD domain with the histone H3 tail Zhang, Y., Jurkowska, R., Soeroes, S., Rajavelu, A., Dhayalan, A., Bock, I., Rathert, P., Brandt, O., Reinhardt, R., Fischle, W. & Jeltsch, A Nucleic Acids Research 38, 13 & 4246-4253 2010 11.1
21 The Dnmt3A PWWP domain reads histone 3 lysine 36 trimethylation and guides DNA methylation Dhayalan, A., Rajavelu, A., Rathert, P., Tamas, R., Jurkowska, RZ., Ragozin, S. & Jeltsch, A. The Journal of Biological Chemistry 285, 34 & 26114-26120 2010 4.1
22 A continuous protein methyltransferase assay for enzyme activity measurement and inhibitor screening Dhayalan, A., Dimitrova, E., Rathert, P. & Jeltsch, A. Journal of Biomolecular Screening 14, 9 & 1129-1133 2009 2.5
23 The ankyrin repeat domain of Huntingtin interacting protein 14 contains a surface aromatic cage, a potential site for methyl-lysine binding Gao, T., Collins, R.E., Horton, J.R., Zhang, X., Zhang, R., Dhayalan, A., Tamas, R., Jeltsch, A. & Cheng, X. Proteins 76, 3 & 772-777 2009 2.3
24 Specificity of protein lysine methyltransferases and methods for detection of lysine methylation of non-histone proteins Rathert, P., Dhayalan, A., Ma, H. & Jeltsch, A. Molecular BioSystems 4, 12 & 1186-1190. 2008 2.9
25 Protein lysine methyltransferase G9a acts on non-histone targets Rathert, P., Dhayalan, A., Murakami, M., Zhang, X., Tamas, R., Jurkowska, R.Z., Komatsu, Y., Shinkai, Y., Cheng, X. & Jeltsch, A. Nature Chemical Biology 4, 6 & 344-346 2008 12.2
26 Mapping of protein-protein interaction sites by the ‘Absence of Interference’ approach. Dhayalan, A., Jurkowski, T.P., Laser, H., Reinhardt, R., Cheng, X., Jia, D. & Jeltsch, A. Journal of Molecular Biology 376, 4 & 1091-1099 2008 5.1

Papers Published in Conference Proceedings

S.No Title Name of the Authors as per the order in Paper Details of Conference Publication Page Nos. Year

Books

S.No Title of the Book Name of the Authors as per the order in Book Publisher Year ISBN No.

Chapters in Books

S.No Title of the Chapters Name of the Authors Title of the Book Publisher Year ISBN No.

Edited Books

S.No Title of the Book Name of the Authors as per the order in Book Publisher Year ISBN No.

Ongoing Projects

S.No Title of the Project Sponsored By Period Sanctioned Amount(Rs. Lakh) Year
1 Investigating the substrate specificity profile of human Protein Arginine Methyltransferase 6 (PRMT6) and identification of new substrates BRNS 2018 to 2021 33.7 2018
2 Substrate specificity of human SET7/9lysine methyltransferase and identification of new substrates SERB-DST 2018 to 2021 44.4 2018

Ongoing Consultancy Works

S.No Title of the Consultancy Work Sponsored By Period Sanctioned Amount(Rs. Lakh) Year

Completed Projects

S.No Title of the Project Sponsored By Period Sanctioned Amount(Rs. Lakh) Year
1 Screening and evaluation of Tudor domains and other chromatin associated proteins for the specific recognition of histone arginine modifications DBT 2016 to 2019 44.4 2016
2 Screening and evaluation of Tudor domains and other chromatin associated proteins for the specific recognition of histone arginine modifications DBT 2016 to 2019 44.4 2016
3 Identification and Characterization of novel interaction partners of the protein lysine methyltransferase, SMYD2 CSIR 2013 to 2016 18.84 2013
4 Identification and Characterization of novel regulatory proteins for the human protein lysine methyltransferase, SET7/9 SERB-DST 2012-2015 23.4 2012
5 Regulation of Mammalian Protein Arginine Methyltransferase Activity DBT 2011 to 2014 41.2 2011
6 Biochemical and Functional Characterization of Histone Arginine Methylation UGC 2011 to 2014 11.47 2011

Completed Consultancy Works

S.No Title of the Consultancy Work Sponsored By Period Sanctioned Amount(Rs. Lakh) Year

Career Guidance Offered to students

S.No Name of the Scheme No. of Students Competitive Examinations/ Career Counseling No. of Students Passed No. of Students Placed

List of capability enhancement such as Soft skill development, Remedial coaching, Language lab,
Bridge courses, Yoga, Meditation, Personal Counselling and Mentoring etc.,

S.No Name of the Programme/Scheme Date of Implementation No. of Students Enrolled Agencies Involved

Research Guidance - PG

S.No Year Degree No. of Students Awarded Department/Centre
1 2019 M.SC 2 Biotechnology
2 2018 M.SC 1 Biotechnology
3 2017 M.SC 3 Biotechnology
4 2016 M.SC 2 Biotechnology
5 2015 M.SC 3 Biotechnology
6 2014 M.SC 2 Biotechnology
7 2013 M.SC 3 Biotechnology
8 2012 M.SC 4 Biotechnology
9 2011 M.SC 1 Biotechnology

Research Guidance - Ph.D

S.No Student Name Registration Date Registration No. Thesis Title Thesis Submitted Status Thesis Submitted Date Vivavoce Completed Status Date Awarded
1 Mamta Verma 29-07-2011 R25766 Identification and Chracterization of interaction partners for human Protein Arginine Methyltransferase, PRMT7 and PRMT3 YES 04-10-2017 YES 02-04-2018
2 Sharad Awasthi 25-10-2011 R27561 Biochemical and Functional Characterization of human proteins, DDX49 and LOC102288414 YES 08-01-2018 YES 03-05-2018
3 Mohd. Imran K Khan 19-08-2013 R33846 Identification and Chracterization of interaction partners for human enzyme, SmyD2 YES 11-05-2020 NO
4 Somlee Gupta 12-07-2017 R44856 Functional Chracterization of human protein, FUBP1 NO NO
5 Arun. M 07-08-2012 R29258 Functional Characterization of human proteins, SET7/9 and SMN1 YES 25-03-2019 YES 20-12-2019
6 C. Baskar 04-06-2012 R27948 Uncharacterized protein, FAM47E regulates the functions of Protein Arginine Methyltransferase 5 (PRMT5) YES 03-10-2018 YES 16-03-2020

Research Guidance - Post Doctoral

S.No Scholar Name Designation Funding Agency Fellowship Title Year of Joining Year of Completion

Financial assistance availed to attend conferences / workshops and to pay membership fee
of professional bodies during the year

S.No Conference/ workshop attended for which financial support provided Professional body for which membership fee is provided Amount of Support Place From Date To Date Year

E-Lecture Details

S.No E-Lecture Title Development of e-content/e-learning/delivering Member of Editorial Bodies Reviewer/Referee of
Content/Module Title Institution/Platform Year Weblink

Details of Online Education Conducted

S.No Nature of Online Course No. of Sessions Target Group Date

Invited Talks in Conference/Seminar/Workshop/Training Programme

S.No Title of the Paper Conferences/Seminar/Workshop/Training Programme Organized by Whether International / National / State / Regional / College or University Level From To Year
1 The RNA helicase, DDX49 regulates the global translation 10th RNA Group Meeting Rajiv Gandhi Centre for Biotechnology, Trivandrum National 02-05-2019 04-05-2019 2019
2 Histone methylation signalling and the functional characterization of RNA helicase, DDX49 National Conference on Drug Discovery and Translational Medicine Department of Biochemistry & Biotechnology, Annamalai University, Chidambaram National 14-03-2019 16-03-2019 2019
3 Quantitative Real time PCR methods and applications 5th National workshop on Real Time PCR and HPLC Techniques in Biomedical Research CIDRF, Sri Balaji Vidyapeeth, Puducherry National 29-11-2018 29-11-2018 2018
4 Epigenetic Signalling and RNA helicase in Cancers National Seminar on Recent Advances in Medical Research Department of Biomedical Science, Bharathidasan University National 07-03-2018 07-03-2018 2018
5 Histone arginine methylation mediated epigenetic signaling and the functional characterization of a International Conference on Current Trends and Emerging Challenges in Biological Sciences D.K.M College, Vellore International 15-02-2018 16-02-2018 2018
6 Epigenetic roles of histone arginine methylation and the functional characterization of a RNA helica National Conference on Environment, Health and Disease CIDRF, Sri Balaji Vidyapeeth, Puducherry National 12-02-2018 12-02-2018 2018
7 Epigenetic and Metabolic Functions of Arginine Methylation and Protein Arginine Methyltransferases National Seminar on Current Topics in Biological Research Department of Biochemistry and Molecular Biology, Pondicherry University National 20-10-2017 20-10-2017 2017
8 Quantitative Analysis of Biological Data DBT Sponsered Training course on Fermentation and Bioseperation Methods Department of Microbiology, Pondicherry University National 07-01-2015 07-01-2015 2015
9 Application of peptide arrays in Epigenetics and Molecular biology National Seminar on Clinical Proteomics for Veterinary and Allied Sciences Rajiv Gandhi Institute of Veterinary Education and Research, Puducherry. National 18-07-2014 19-07-2014 2014
10 Peptides in Epigenetics Research National Conference on Bioactive Peptides Madras Veterinary College, Chennai National 18-12-2014 19-12-2014 2014
11 Overview of epigenetic Signalling National Workshop on Quest 2013 Department of Marine Biotechnology, Bharathidasan University National 21-10-2013 25-10-2013 2013
12 Bichemistry of epigenetic signalling National Seminar on Biochemistry in Health and Environment St. Josephs College of Arts and Science, Cuddalore National 09-03-2013 09-03-2013 2013
13 Role of epigenetics in Health and Disease International Conference on Environmental Security for Food and Health M.D.T. Hindu College, Tirunelveli and EPS Global Medical development Inc., Canada International 16-02-2012 18-02-2012 2012

Conferences/Seminars Organized

S.No Title of the Programme Sponsors Venue & Duration Whether International / National / State / Regional / College or University Level From To Year
1 National Science Day Celebration in Department of Biotechnology Pondicherry University Centre For Bioinformatics & One Day University 17-04-2017 17-04-2017 2017

Workshop Organized

S.No Title of the Programme Sponsors Venue & Duration Whether International / National / State / Regional / College or University Level From To Year

Administrative Responsibilities in the Government and Quasi Government Agencies

S.No Name of the Position Agency/Organisation Duration Nature of Duties

Affiliation in Academic Bodies/Societies

S.No Name of the Body/Society Nature of Affiliation Year
1 UG and PG Board of Studies, Department of Biotechnology, Pondicherry University Internal Member 2017
2 Board of Studies, Centre for Bioinformatics, Pondicherry University External Member 2016
3 Indian Association of Biomedical Scientists Life Member 2015
4 Board of Studies, Centre for Bioinformatics, Pondicherry University External Member 2014
5 UG and PG Board of Studies, St. Josephs College of Arts and Science (Autonomous) External Expert 2014
6 UG and PG Board of Studies, St. Josephs College of Arts and Science (Autonomous) External Expert 2012

Participation & Extension Activities (Academic/Administraion)

S.No Name of the Position (Head, Dean, Co-ordinator, Director, etc.,) Duration Nature of Dutites
1 Member in Stock verification committee 2 days (2013) To verify the stocks in the Department
2 Member in Selection Committee 1 day (2014) To interview the candidates for Project fellow position
3 Member in Selection Committee 1 day (2014) To interview the candidates for JRF in DST project
4 Member in Stock verification committee 2 days (2016) To verify the stocks in the Department
5 Member in Selection Committee 1 day (2018) To interview the candidates for JRF & SRF positions

Participation & Extension Activities (Co-Curricular)

S.No Name of the Position (NSS, NCC, Warden etc.,) Duration Nature of Dutites
1 Observer in Students Election 1 day (2014) Observe the election process
2 Election Officer in Life Science 3 days (2016) To conduct the Students Election
3 Election Officer in Life Science 3 days (2017) To conduct the Students Election
4 Observer in BINC Examination 2 days (2015) To observe the National Examination Process
5 Observer in BINC Examination 2 days (2017) To observe the National Examination Process
6 Coordinator of M.Sc students Seminar 8 weeks in 2015 (2 or 3 hours per week) To facillate and conduct M.Sc students seminar in the Department
7 Coordinator of M.Sc students Seminar 13 weeks in 2016 (2 or 3 hours per week) To facillate and conduct M.Sc students seminar in the Department
8 Coordinator of M.Sc students Seminar 7 weeks in 2018 (2 or 3 hours per week) To facillate and conduct M.Sc students seminar in the Department
9 Doctoral Committee Member 10 meetings (2 hours duration) in 2011 to 2012 To monitor the research progress of the Ph.D students
10 Doctoral Committee Member 12 meetings (2 hours duration) in 2013 To monitor the research progress of the Ph.D students
11 Doctoral Committee Member 18 meetings (2 hours duration) in 2014 To monitor the research progress of the Ph.D students
12 Doctoral Committee Member 17 meetings (2 hours duration) in 2015 To monitor the research progress of the Ph.D students
13 Doctoral Committee Member 20 meetings (2 hours duration) in 2016 To monitor the research progress of the Ph.D students
14 Doctoral Committee Member 25 meetings (2 hours duration) in 2018 To monitor the research progress of the Ph.D students
15 Doctoral Committee Member 3 meetings (2 hours duration) in 2018 To monitor the research progress of the Ph.D students

Collaboration with Institution/Industry

S.No Collaborator Name Designation Institution/Industry Type Nature of Collaboration Period of Collaboration Visits to Collaborating
Institution / Industry
Details of Collaborative Research/Teaching
From Date To Date From Date To Date

Faculty Development Programme Attended (Orientation, Refresher, other Short Term Course during the year)

S.No Title of the FDP Organiser Venue Duration From Date To Date Year

Details of Executive Development Prog/Management Development Prog. conducted

S.No Name of the Programme No. of Participants Venue Duration From Date To Date Year Revenue Generated

Participation in IMPESS, IMPRINT, SPARC, STARS, LEAP Programme etc and DSF Funding Programme

S.No IMPRESS/IMPRINT/SPARC/STARS/LEAP/Others Place From Date To Date Year

Enrolment under ARPIT Programme

S.No Name of the Programme Period of the Programme
From Date To Date