Dr. H.Surya Prakash Rao

Department of Chemistry
Date Of Joining: 
20-08-1988 (Reader); 01-09-1997 (Professor)
DegreeSpecializationUniversity / InstitutionYear of Completion
Total Experience: 
1985-present (Teaching); 1975 to present (Research)
Area of Specialization/Interest: 


Synthetic Organic Chemistry, Heterocyclic Chemistry, Chemistry of Organic Molecules of Medicinal Interest, Organic Reactions and Reagents.

Publications (in last 3 years): 


Publications in refereed journals:                      133

Publications of review articles:                          10

Presentation in conferences:                             173

No. of scholars who took Ph.D.:                        19

No. of scholars who took M.Phil.:                     26

Patents :                                                              03


Publications (for past 10 years)

133. Copper (cat) and phenylboronic acid mediated deformylative C-N coupling of isoindolinone-3-ols with formamides provide C(3) aminoisoindolinones Rao, H. S. P.; J PRABHAKARAN, SILAMBARASAN KANNIYAPPAN and A VEERA BHADRA RAO J. Chem. Sci. 2018 DOI.org/10.1007/s12039-018-1474-8. Special Section on Transition Metal Catalyzed Synthesis of Medicinally Relevant Molecules.

132. Vinylogous Blaise reaction: Conceptually new synthesis of 2-pyridones Rao, H. S. P.; Muthanna, N and Ashiq Hussain Padder Synlett 2018 Manuscript accepted (ST-2018-04-0222-L.R1).Officially qualified for the SYNLETT Best Paper Award.

131. One-Pot Synthesis of Densely Substituted Pyrazolo[3,4-b]-4,7-dihydropyridinesH Rao, H. S. P.; Lakshmi Narayana Adigopula, and Krishna Ramadas ACS Comb. Sci., 2017, DOI: 10.1021/acscombsci.6b00156.

130. Synthesis and characterization of bridged morpholine derivatives fused to a phenanthrene ring system Rao, H. S. P.; Vijjapu, S. J. Che, Res. 2017, 000

129. In-silico and in-vitro anti-cancer potential of a curcumin analogue (1E, 6E)-1, 7-di (1H-indol-3-yl) hepta-1, 6-diene-3, 5-dione,SA Sufi, LN Adigopula, SB Syed,V Mukherjee, MS Coumar, Rao, H. S. P., R Rajagopala, Biomedicine & Pharmacotherapy 2017, 85, 389–398

128.  Synthesis, characterization and antituberculotic evaluation of conjugates of ciprofloxacin / moxifloxacin and fluorescent coumarin, Rao, H. S. P.; Desai, A.; Rao, A. V. B. Ind. J. Chem. Section B. 201756B, 87-95.

127. Synthesis and  characterization of H-cardanol-triazole and fructose/galactose/mannose conjugates, Rao, H. S. P.; Kamalraj, M. Ind. J. Chem201785, 000-000

127. Iodine-catalyzed dehydrative-cycloisomerization of pent-4-yne-1,2-diols to di- and tri-substituted furans, Rao, H. S. P.; Vijjapu, S.submitted for publication 

126. The quorum sensing molecule N-acyl homoserine lactone produced by Acinetobacter baumannii displays antibacterial and anticancer properties,J John, R Saranathan, LN Adigopula, V Thamodharan, S P Singh, T P Lakshmi, M A Charan Tej, R S Rao, R Krishna, Rao, H. S. P & K. Prashanth, Biofouling, 2016,32, 1029–1047

125. Variations in the Blaise reaction: Synthesis of 3,5-diketopentanoates and 3-amino-5-oxopent-3-enoates, Rao, H. S. P.; Muthanna, N.Synlett. 2016; 27(13): 2014-2018.

124. Synthesis and antimicrobial evaluation of 2-hydroxynaphthalene-1,4-dione and 4H-chromene conjugates, Rao, H. S. P.; Tangeti, V. S.; Adigopula, L. N. Research on Chemical Intermediates, 2016, 42,7285-7303

123. Synthesis, in vitro and in silico anti-proliferative activity of 4-aryl-4H-chromene derivatives, Parthiban, A.; Kumaravel, M.: Muthukumaran, J.; Rukkumani, R.; Krishna, R.; Rao, H. S. P. accepted for publication in Med. Chem. Res. 2016, 26, 000

122. Copper-mediated arylation with arylboronic acids: Facile and modular synthesis of triarylmethanes, Rao, H. S. P.; Rao, A. V. B. Beilstein J. Org. Chem. 2016, 12, 496–504

121. Copper(II) bromide catalyzed C-C/C-N bond forming reactions: Synthesis of pyrrole incorporated triarylmethanes, Rao, H. S. P.; Rao, A. V. B.; Sivakumar, S. Syn. Commun. 2015, DOI: 10.1080/00397911.2015.1100746.

120. Synthesis and stereochemistry of cis-2,6-diphenyl-1-alkylpiperidines, Rao, H. S. P.; Poonguzhali, Tetrahedron Lett, 2015, 56, 6190-6193.

119. Synthesis, in vitro and in silico antimalarial activity of 7-chloroquinoline and 4H-chromene conjugates Parthiban, A.; Muthukumaran, J.; Krishna, R.; Rao, H. S. P. Bioorg. Med. Chem. Lett. 2015, 25, 4657-4663.



Seminars/Conferences/Workshops Conducted(Last 3 Years): 
Year Programme     Sponsor Position held
2008 Two-day Green Chemistry Workshop DST Coordinator
2008 Refresher Course in Chemistry Academic Staff College, Pondicherry University Coordinator


Seminars/Conferences/Workshops Participated(Last 3 Years): 



Level of Participation

         Title of Programme (International/National/Institution)

  • Organo copper reagents in organic synthesis, invited lecture School of Chemistry, University of  Hyderabad, on 13th Feb, 2015.

  • About Science, Scientists and Research – invited lecture given to students under DST Inspire program on 22-01-2015 at Department of Physics, University of Mysore, Mysore, Karnataka on 22 January, 2015.

Honours / Awards (if any): 
Year Details of award / Prize Contribution for which awarded
2008 Bronze Medal – Chemical Research Society of India Research Contribution during recent past
Academic Distinctions:
  • National Merit Citation, 1969; National Associate Award, UGC, India, 1985-88.
  • S.I. Perumal Endowment Award, 1997.
  • Visiting Professor, North-Eastern Hill University, Shillong, Meghalaya, May-June, 1998.
  • Editorial Board Member, Ind J. Het. Chem., J. Che. Sci, Arkivoc and ISRN Organic Chemistry.
  • CRSI award (2008); NSR Center Award, University of Nijmegen, The Netherlands (1999-2000 & 2002).
  • National Organic Symposium Trust 2007-2011 – Council member; CRSI – Council Member.
  • IGNOU – Expert in Organic Chemistry; NAAC –  National Panel of Experts
Projects Undertaken: 

Research Background:

Ph.D.: Indian Institute of Science, Bangalore, 1975-80.
PDF: Rice University, Houston 1980-82; University of Minnesota, Minneapolis 1982-84 and University of Hyderabad, Hyderabad 1984-85.
Visiting Scientist: University of Nijmegen, The Netherlands, 1999-2000, 2002 and Taiwan 2007.

Current Research Interests:
Synthesis and stereochemistry of sulfur, nitrogen and oxygen heterocycles; Synthetic applications of the Blaise Reaction.

Institution/Dept. Development Activities: 

Contact Details
Present Address: 
Professor Department of Chemistry Pondicherry University Puducherry - 605 014 INDIA Tel: O:91 413 2654411; R: 91-413-2252080; 94432 64222 E-mail: hspr@yahoo.com; hspr.che@pondiuni.edu.in Fax: +91-413-2656 230 E-Mail: hspr.che@pondiuni.edu.in; hspr@yahoo.com,
Telephone No: 
hspr.che@pondiuni.edu.in, hspr@yahoo.com

19.       Nandurka Muthanna, Variations and synthetic applications of the blaise reaction: synthesis of 1,3-diketones, 3-amino enones, 3,5-diketo esters, 2-pyridones and dibenzopyrans, December 2015.

18.       Satish, V. Synthetic and mechanistic studies on phenanthrene-9,10-dione, pyrene-4,5-dione and acenaphthylene-1,2-dione, June, 2015.

17.       Kamalraj, M. Chemistry of H-Cardanol Derivatives, April, 2015.

16.       Veera bhadra Rao, A. Copper mediated Csp3-Csp2 cross coupling reactions: Synthesis of 4-aryl-4H-chromenes, 3-substituted isoindolinones and triarylmethanes, March, 2015.

15.       Parthiban, A. Synthesis, characterization and biological activity of 4H-chromenes and 1,4-dihydropyridines, January, 2015.

14.       Desai, Avinash, Synthesis and characterization of trisubstituted pyrroles and conjugates of coumarin-bioactive molecules – January 2015.

13.       Guruvaiah, C. Studies on Acetylene-Azide Cycloadditions: Development of new methods for the CuAAC click reaction and synthesis of phenol / porphyrin based dendrimers with multiple cholesterol units – 2014.

12.       Venkata Swamy Tangeti, Synthetic Studies on Oxygen Heterocycles: Conjugates / Hybrids of Coumarins, Chromenes, Flavanones and Pyranones – 2013.

11.       Vasantham, K. Novel and expedient approach to polysubstituted thiophenes and pyrroles – 2009.

10.       S. Rafi, Studies on the synthesis and stereochemistry of selected saturated hetero-cycles – 2008.

09.       K. Geetha, Nitroketene N,S-acetal route to fictionalized 4H-chromenes and further transformation into hybrid amino acids and DOPA isomers – 2008.

08.       S. Sivakumar, Ketene Dithioacetal Chemistry: Synthesis of coumarins, pyrroles and orthoesters – 2008.

07.       E. Poonguzhali, Reductive Amination Cyclization Route to Nitrogen Heterocycles: Studies in the Synthesis and Stereochemistry of Piperidines, Pyrrolidines and 8-Azasteroids – 2008.

06.       S. Jothilingam, Microwave-mediated Organic Reactions: Studies on Pyrrole / Furan Synthesis and Michael / Retro-Michael Reactions, 2004.

05.       S. P. Senthilkumar, Studies in the Synthesis of Nitrogen Heterocycles and Carbocycles, 2003.

04.       S. Rajamathe, Diastereoselection in the Benzylation of Cyclic -Ketoester Enolates: Remote Substituent Effects, 2003.

03.       K. Jeyalakshmi, Studies in Organic Synthesis: Synthetic Elaborations on Chalcone, Phenyl vinyl ketone, dibenzoyl ethylene and their derivatives, 1999.

02.       B. Bharathi, Synthetic and Stereochemical Investigations of Biologically Important Heterocyclic Compounds, 1995.

01.       K. Subba Reddy, Studies in Stereochemistry:  Stereoselectivity in Cyclic -Ketoester Alkylations and Cyclic Enone Reductions, 1994.